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terminal complement inhibition

Showing 1 - 25 of 4,563
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Paroxysmal Nocturnal Hemoglobinuria Trial in China (Crovalimab)

Active, not recruiting
  • Paroxysmal Nocturnal Hemoglobinuria
  • Changchun City, China
  • +5 more
Jul 11, 2022

Covid19, Thrombotic Microangiopathies, Acute Kidney Injury Trial in Boston (Ravulizumab)

Active, not recruiting
  • Covid19
  • +2 more
  • Boston, Massachusetts
    Brigham and Women's Hospital
Dec 31, 2022

Traumatic Brain Injury, Trauma, Head Trial in Den Haag, Leiden, Rotterdam (C1 Inhibitor, Human, Placebo)

Recruiting
  • Traumatic Brain Injury
  • Trauma, Head
  • C1 Inhibitor, Human
  • Placebo
  • Den Haag, Netherlands
  • +2 more
Sep 6, 2021

COVID-19 Trial in Belgium (Zilucoplan®, Placebo)

Completed
  • COVID-19
  • Aalst, Belgium
  • +8 more
Jan 26, 2022

Generalized Myasthenia Gravis Trial in United States

Recruiting
  • Generalized Myasthenia Gravis
    • Phoenix, Arizona
    • +9 more
    Dec 16, 2020

    Autoimmune Haemolytic Anaemia Trial in Worldwide (BIVV020)

    Active, not recruiting
    • Autoimmune Haemolytic Anaemia
    • Essen, Germany
    • +4 more
    Jan 19, 2023

    C3 Glomerulopathy, Membranoproliferative Glomerulonephritis, Complement Abnormality Trial in Sweden (Aliskiren, Enalapril)

    Recruiting
    • C3 Glomerulopathy
    • +4 more
    • Gothenburg, Sweden
    • +3 more
    Jan 4, 2022

    Atypical Hemolytic Uremic Syndrome Trial in Ranica (cemdisiran, Placebos)

    Withdrawn
    • Atypical Hemolytic Uremic Syndrome
    • Ranica, BG, Italy
      Centro di Ricerche Cliniche per le Malattie Rare " Aldo e Cele D
    Mar 8, 2021

    Vasculitis, Systemic Lupus Erythematosus (SLE) Trial in Allschwil (CCX168, Placebo)

    Completed
    • Vasculitis
    • Systemic Lupus Erythematosus (SLE)
    • Allschwil, Switzerland
      Covance Clinical Research Unit (CRU) AG
    Aug 2, 2023

    Coronavirus Trial (Eculizumab)

    Available
    • Coronavirus
    • (no location specified)
    Mar 26, 2020

    First in Man Study to Evaluate Initial Safety Trial in Leeds (GL-0719, Placebo)

    Recruiting
    • First in Man Study to Evaluate Initial Safety
    • Leeds, United Kingdom
      Labcorp Clinical Research Unit Ltd
    Sep 9, 2022

    Community-acquired Pneumonia Trial (AON-D21, Placebo)

    Not yet recruiting
    • Community-acquired Pneumonia
    • (no location specified)
    Jul 25, 2023

    Antibody-mediated Rejection, Hyperacute Rejection of Cardiac Transplant, Left Ventricular Dysfunction Trial in Los Angeles

    Completed
    Has Results
    • Antibody-mediated Rejection
    • +4 more
    • Los Angeles, California
      Cedars Sinai Medical Center, Heart Institute
    Apr 30, 2021

    Bullous Pemphigoid Trial in Worldwide (nomacopan (rVA576), Placebo)

    Withdrawn
    • Bullous Pemphigoid
    • nomacopan (rVA576)
    • Placebo
    • Los Angeles, California
    • +11 more
    Oct 18, 2022

    Complement C5a Receptors in Hidradenitis Suppurativa

    Recruiting
    • Hidradenitis Suppurativa
      • Redwood City, California
        Stanford University
      Jun 27, 2022

      Paroxysmal Nocturnal Hemoglobinuria Trial in China

      Recruiting
      • Paroxysmal Nocturnal Hemoglobinuria
        • Hefei, Anhui, China
        • +23 more
        Nov 23, 2023

        C3G Trial in Worldwide (Placebo, iptacopan)

        Recruiting
        • C3G
        • Aurora, Colorado
        • +60 more
        Nov 23, 2022

        Thrombotic Microangiopathy Associated With Mitomycin C, Treated

        Recruiting
        • Thrombotic Microangiopathies
          • Strasbourg, France
            Service de Néphrologie, Dialyse et Transplantation - CHU de Stra
          Oct 18, 2023

          SGLT2 Inhibition in Heart Failure

          Recruiting
          • Heart Failure
          • Sodium-glucose cotransporter 2 inhibitor
          • Belfast, United Kingdom
            Belfast Health and Social Care Trust
          Nov 15, 2023

          PNH, Hemolysis Trial in Beijing (CAN106 20 mg/kg, CAN106 40 mg/kg, CAN106 80 mg/kg)

          Recruiting
          • PNH
          • Hemolysis
          • CAN106 20 mg/kg
          • +2 more
          • Beijing, Beijing, China
            Peking Union Medical College Hospital
          Sep 10, 2022

          Healthy Trial in Neu-Ulm (Intravenous AON-D21, Intravenous )

          Completed
          • Healthy
          • Intravenous AON-D21
          • Intravenous placebo
          • Neu-Ulm, Germany
            Nuvisan GmbH
          Jan 11, 2022

          Periodontal Diseases Trial in Chennai (Non surgical periodontal therapy)

          Not yet recruiting
          • Periodontal Diseases
          • Non surgical periodontal therapy
          • Chennai, Tamilnadu, India
          • +1 more
          Apr 26, 2023

          Pharmacodynamics of Eculizumab in Paroxysmal Nocturnal

          Completed
          • Paroxysmal Nocturnal Hemoglobinuria
          • +2 more
          • Blood collection for measurement of eculizumab peak concentrations
          • Nijmegen, Netherlands
            Radboudumc
          Aug 23, 2022

          Preeclampsia, Severe Preeclampsia, Eculizumab Trial in Los Angeles (Eculizumab)

          Suspended
          • Preeclampsia
          • +11 more
          • Los Angeles, California
            Cedars-Sinai Medical Center
          Jun 16, 2022

          Pulmonary Arterial Hypertension Trial in Calgary, Quebec City (Apabetalone)

          Completed
          • Pulmonary Arterial Hypertension
          • Calgary, Alberta, Canada
          • +1 more
          Apr 22, 2022